Basic Information

Symbol
hsa-mir-450a-2
RNA class
miRNA miRNA hairpin
Alias
MIR450A2 MicroRNA 450a-2 Hsa-MiR-450a-5p Hsa-Mir-450a-2 Hsa-Mir-450-2 MicroRNA 450-2 MIRN450-2 MIRN450A2 Hsa-Mir-450-P1_pre Hsa-MiR-450a-2-3p MIMAT0031074 MIMAT0001545 MIRN450A-2 Mir-450a-2 MI0003187
Location (GRCh38)
5:36147892-36147988
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-450a-2
Sequence length
100 nt
GC content
0.2900

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.80 kcal/mol
Thermodynamic ensemble
Free energy: -35.87 kcal/mol
Frequency: 0.1773
Diversity: 3.35
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.........(((((.(((((((...(((((.(((((((((((((((.......))))))))))))))).)))))...))))))).)))))..........
Thermodynamic Ensemble Prediction
{{{......(((((.{((((((...(((((.(((((((((((((((.......))))))))))))))).)))))...))))))}.))))).......}}}
Forensic Context

A study in humans established a multi-class support vector machine (MSVM) classification model for forensic body fluid identification using TaqMan RT-qPCR, which achieved 98% accuracy on an independent test set and demonstrated efficacy on aged casework samples [Li et al. DOI:10.1016/j.fsigen.2024.103180]. A study in rats demonstrated that the mir-450a was downregulated with a 1.67-fold change at 3 and 6 hours following oleic acid-induced acute lung injury [Lee et al. DOI:10.3892/Mmr.2014.2155]. A separate review noted that the mir-450a was differentially expressed in mouse blood 6 hours after γ-irradiation, indicating its potential as a radiation-responsive molecule [Jia & Wang DOI:10.3389/fcell.2022.861451].