Basic Information

Symbol
hsa-mir-4524b
RNA class
miRNA miRNA hairpin
Alias
MIR4524B MicroRNA 4524b Hsa-Mir-4524b MIMAT0022256 MIMAT0022255 MI0019114
Location (GRCh38)
12:124915547-124915659
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4524b
Sequence length
115 nt
GC content
0.4435

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.10 kcal/mol
Thermodynamic ensemble
Free energy: -51.19 kcal/mol
Frequency: 0.0336
Diversity: 17.35
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
......(((({.,.(.((((((,(((.(((((((((((.(((((((((((...,,....,,...))))))))))).))))))))))).))).,}))))}),...,..)))))...
Forensic Context

A study in human postmortem brain tissue demonstrated that the mir-4524b was hypermethylated in the nucleus accumbens of subjects with alcohol use disorder, showing a mean methylation level of 0.498 in cases versus 0.220 in controls [Liu et al. DOI:10.3390/genes13060958].