Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the mir-4524b-5p being one of many dysregulated in these processes [Siu et al. DOI:10.1111/wrr.13100]. A separate forensic study in humans established a multi-class support vector machine model for body fluid identification using 12 key miRNA markers, though the mir-4524b-5p was not among the evaluated or selected markers in this validated workflow [Li et al. DOI:10.1016/j.fsigen.2024.103180]. A study in humans demonstrated that the mir-4524b-5p was differentially expressed and shared across three pairs of monozygotic twins, suggesting its potential role as a biomarker for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].