Basic Information

Symbol
hsa-mir-1246
RNA class
miRNA miRNA hairpin
Alias
MIR1246 MicroRNA 1246 Hsa-Mir-1246 Hsa-MiR-1246 MIRN1246 MIMAT0005898 MI0006381
Location (GRCh38)
2:176600980-176601052
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1246
Sequence length
73 nt
GC content
0.4384

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-18.60 kcal/mol
Thermodynamic ensemble
Free energy: -19.99 kcal/mol
Frequency: 0.8553
Diversity: 0.66
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((..(((...((((((((((((..((((........))))..))))).......))))))))))...)))..
Thermodynamic Ensemble Prediction
(((,.(((...((((((((((((..((((........))))..))))),......,))))))))).,.)))..
Forensic Context

A study in humans demonstrated that the mir-1246 is a saliva-specific microRNA for forensic body fluid identification, showing specificity even against vaginal secretion [Li et al. DOI:10.1007/s00414-021-02678-w]. In a separate review of human skin conditions, the mir-1246 was found to be upregulated in hypertrophic scar tissue compared to normal tissue [Siu et al. DOI:10.1111/wrr.13100].