Basic Information
Symbol
hsa-miR-1246
RNA class
miRNA
mature miRNA
Alias
hsa-miR-1246
MIR1246
MicroRNA 1246
Location (GRCh38)
-
Forensic tag(s)
Tissue/body fluid identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-18.60 kcal/mol
Thermodynamic ensemble
Free energy:
-19.99 kcal/mol
Frequency:
0.8553
Diversity:
0.66
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((..(((...((((((((((((..((((........))))..))))).......))))))))))...)))..
Thermodynamic Ensemble Prediction
(((,.(((...((((((((((((..((((........))))..))))),......,))))))))).,.)))..
Forensic Context
A study in humans demonstrated that the miR-1246 is a saliva-specific microRNA for forensic body fluid identification, showing specificity even against vaginal secretion [Li et al. DOI:10.1007/s00414-021-02678-w]. In a separate review of human skin conditions, the miR-1246 was found to be upregulated in hypertrophic scar tissue compared to normal tissue [Siu et al. DOI:10.1111/wrr.13100].