Basic Information
Symbol
hsa-miR-4644
RNA class
miRNA
mature miRNA
Alias
hsa-miR-4644
MIR4644
MicroRNA 4644
Location (GRCh38)
-
Forensic tag(s)
Tissue/body fluid identification
Drug abuse diagnoses
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-38.30 kcal/mol
Thermodynamic ensemble
Free energy:
-40.26 kcal/mol
Frequency:
0.0415
Diversity:
8.08
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.((.(((((.(((((((((..(((((.(((...........)))..)))))..))).)))))).))).)).)).)))))
Thermodynamic Ensemble Prediction
(((((.((.(((((.(((((((((..(((((.(((...........}})..)))))..)))))))))).))),,).)).)))))
Forensic Context
A study in humans demonstrated that the miR-4644 increased 3.23-fold in serum following recreational alcohol consumption, with this change being part of a broader significant increase in 265 microRNAs [Ten Berg et al. DOI:10.1080/1354750X.2018.1499128]. In forensic body fluid identification research, the miR-4644 was identified as a microRNA with potential for alcohol exposure detection, though its specific performance in differentiating body fluids was not detailed in the examined validation framework for venous blood, saliva, semen, vaginal secretion, and menstrual blood [Sauer et al. DOI:10.1016/j.fsigen.2016.01.018].