Basic Information

Symbol
hsa-mir-4649
RNA class
miRNA miRNA hairpin
Alias
MIR4649 MicroRNA 4649 Hsa-Mir-4649 Hsa-MiR-4649-5p Hsa-MiR-4649-3p MIMAT0019712 MIMAT0019711 MI0017276 Mir-4649
Location (GRCh38)
7:44110849-44110912
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4649
Sequence length
64 nt
GC content
0.6875

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.90 kcal/mol
Thermodynamic ensemble
Free energy: -44.45 kcal/mol
Frequency: 0.4112
Diversity: 2.31
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((((.(((((((((((.(((((((.((.((....)))).)))))))))))))))))))))))
Thermodynamic Ensemble Prediction
.(((((.(((((((((((.(((((((.((.{,....},)).)))))))))))))))))))))))
Forensic Context

A study in humans demonstrated that miRNA expression profiles from blood samples of monozygotic twins show significant differences, with 545 miRNAs found to be differentially expressed across 18 twin pairs. Among these, the mir-4649-5p was identified as a differentially expressed miRNA shared across two pairs of monozygotic twins, suggesting its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].