Basic Information

Symbol
hsa-mir-4662a
RNA class
miRNA miRNA hairpin
Alias
MIR4662A MicroRNA 4662a Hsa-Mir-4662a Hsa-Mir-4662_pre Hsa-MiR-4662a-5p Hsa-MiR-4662a-3p MIMAT0019731 MIMAT0019732 MI0017290
Location (GRCh38)
8:124821985-124822051
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4662a
Sequence length
67 nt
GC content
0.3284

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.50 kcal/mol
Thermodynamic ensemble
Free energy: -36.38 kcal/mol
Frequency: 0.2408
Diversity: 3.51
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((((((((((((.((((((((.((((...)))).)))))))).))))))))))))))))))
Thermodynamic Ensemble Prediction
{(((((((((((((((((.((((((((.{((,...,))).)))))))).)))))))))))))))))}
Forensic Context

A study in humans established a multi-class support vector machine (MSVM) classification model using 12 selected miRNA markers for forensic body fluid identification, achieving 98% accuracy on an independent test set of single-source samples and demonstrating potential for analyzing aged and mixed forensic stains [Li et al. DOI:10.1016/j.fsigen.2024.103180]. A study in humans demonstrated that the mir-4662a-5p was selected from RNA-seq for validation as a potential biomarker for plaque rupture in patients with ST-segment elevation myocardial infarction [Li et al. DOI:10.1016/j.ygeno.2020.11.019].