Basic Information

Symbol
hsa-mir-4674
RNA class
miRNA miRNA hairpin
Alias
MIR4674 MicroRNA 4674 Hsa-Mir-4674 MIMAT0019756 Hsa-MiR-4674 MI0017305
Location (GRCh38)
3:113594876-113594942
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4674
Sequence length
87 nt
GC content
0.8276

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.60 kcal/mol
Thermodynamic ensemble
Free energy: -50.12 kcal/mol
Frequency: 0.4288
Diversity: 4.13
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans identified the mir-4674 as downregulated in whole blood of patients with recurrent myocardial infarction after percutaneous coronary intervention, with this differential expression remaining significant after false-discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307]. Another human study analyzing monozygotic twins found the mir-4674 to be differentially expressed and shared across two pairs of twins, indicating its potential as a biomarker for distinguishing genetically identical individuals in forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].