Basic Information
Symbol
hsa-miR-4674
RNA class
miRNA
mature miRNA
Alias
hsa-miR-4674
MIR4674
MicroRNA 4674
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
Individual identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.60 kcal/mol
Thermodynamic ensemble
Free energy:
-50.12 kcal/mol
Frequency:
0.4288
Diversity:
4.13
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A study in humans identified the miR-4674 as downregulated in whole blood of patients with recurrent myocardial infarction after percutaneous coronary intervention, with this differential expression remaining significant after false-discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307]. Another human study analyzing monozygotic twins found the miR-4674 to be differentially expressed and shared across two pairs of twins, indicating its potential as a biomarker for distinguishing genetically identical individuals in forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].