Forensic Context

A study in humans demonstrated that the mir-4694-5p was differentially expressed in blood samples from monozygotic twins, being shared across two pairs of twins in a microarray analysis, suggesting its potential role in distinguishing genetically identical individuals for forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003]. In a separate human study, the mir-4694-5p was identified as upregulated in the peripheral blood of patients with sepsis compared to healthy controls, indicating its role as a diagnostic biomarker for this condition [Xu et al. DOI:10.3892/mmr.2022.12850].