Basic Information

Symbol
hsa-mir-4700
RNA class
miRNA miRNA hairpin
Alias
MIR4700 MicroRNA 4700 Hsa-Mir-4700 Hsa-MiR-4700-5p Hsa-MiR-4700-3p MIMAT0019796 MIMAT0019797 MI0017333 Mir-4700
Location (GRCh38)
12:120723193-120723266
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4700
Sequence length
74 nt
GC content
0.5541

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-33.90 kcal/mol
Thermodynamic ensemble
Free energy: -35.01 kcal/mol
Frequency: 0.1647
Diversity: 3.82
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...(((....((((((.((((((..((..((((((.......))))))..))))))))))))))..))).....
Thermodynamic Ensemble Prediction
,{.(((....((((((.((((({.,((..((((((.......))))))..))))))))))))))..))),....
Forensic Context

A study in humans with coronary artery disease identified the mir-4700-3p as a biomarker for recurrent myocardial infarction risk, where it was downregulated in whole blood of patients with recurrent MI compared to those without, with this differential expression remaining significant after false-discovery rate correction (FDR <0.1) [Onuoha et al. DOI:10.1111/cts.13307]. A study in humans demonstrated that the mir-4700-3p was differentially expressed and shared across two pairs of monozygotic twins, as identified through miRNA microarray analysis of blood samples from 18 Han Chinese twin pairs [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].