Forensic Context

A study in humans with coronary artery disease identified the miR-4700-3p as a biomarker for recurrent myocardial infarction risk, where it was downregulated in whole blood of patients with recurrent MI compared to those without, with this differential expression remaining significant after false-discovery rate correction (FDR <0.1) [Onuoha et al. DOI:10.1111/cts.13307]. A study in humans demonstrated that the miR-4700-3p was differentially expressed and shared across two pairs of monozygotic twins, as identified through miRNA microarray analysis of blood samples from 18 Han Chinese twin pairs [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].