Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like the mir-4707-5p showing altered expression patterns in human skin tissue samples post-burn and in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-4707-5p was identified as a differentially expressed microRNA shared across three pairs of monozygotic twins, suggesting its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].