Basic Information

Symbol
hsa-mir-4716
RNA class
miRNA miRNA hairpin
Alias
MIR4716 MicroRNA 4716 Hsa-Mir-4716 Hsa-MiR-4716-5p Hsa-MiR-4716-3p MIMAT0019826 MIMAT0019827 MI0017350 Mir-4716
Location (GRCh38)
11:118910708-118910787
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4716
Sequence length
84 nt
GC content
0.4524

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-62.50 kcal/mol
Thermodynamic ensemble
Free energy: -63.58 kcal/mol
Frequency: 0.1727
Diversity: 4.38
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((((((((((((((((((((((((((((((((((((((....))))))},..}}))))))))))))))))))))))))))))))
Forensic Context

A study in humans identified the mir-4716-3p as a circulating microRNA significantly correlated with all-cause mortality in acute myocardial infarction patients, where it served as an independent prognostic factor with an area under the curve greater than 0.75 for predicting 60-month overall survival [Wang et al. DOI:10.1186/s40364-024-00690-x].