Basic Information

Symbol
hsa-mir-4725
RNA class
miRNA miRNA hairpin
Alias
MIR4725 MicroRNA 4725 Hsa-Mir-4725 Hsa-MiR-4725-5p Hsa-MiR-4725-3p MIMAT0019844 MIMAT0019843 MI0017362 Mir-4725
Location (GRCh38)
17:31575269-31575358
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4725
Sequence length
90 nt
GC content
0.6333

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-42.90 kcal/mol
Thermodynamic ensemble
Free energy: -44.94 kcal/mol
Frequency: 0.0365
Diversity: 9.27
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((((((((....(((.(((..((((((((((...(((.(((....))).)))...)))))))))))..))).)))....)))))}})))
Forensic Context

A study in humans identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like hsa-miR-21 and hsa-miR-31 altering fibroproliferative markers and cell behaviors post-burn [Siu et al. DOI:10.1111/wrr.13100]. In a separate human study investigating recurrent myocardial infarction risk, 164 miRNAs were differentially expressed in whole blood, with 69 remaining significant after false-discovery rate correction, and whole blood was identified as a preferred sample source over plasma for miRNA profiling [Onuoha et al. DOI:10.1111/cts.13307]. A study in humans demonstrated that the mir-4725-3p was differentially expressed and shared across three pairs of monozygotic twins, indicating its potential as a biomarker for distinguishing genetically identical individuals in forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].