Basic Information

Symbol
hsa-mir-4745
RNA class
miRNA miRNA hairpin
Alias
MIR4745 MicroRNA 4745 Hsa-MiR-4745-5p Hsa-Mir-4745 Hsa-MiR-4745-3p MIMAT0019878 MIMAT0019879 MI0017384 Mir-4745
Location (GRCh38)
19:804940-805001
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4745
Sequence length
62 nt
GC content
0.8065

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-30.40 kcal/mol
Thermodynamic ensemble
Free energy: -30.80 kcal/mol
Frequency: 0.5266
Diversity: 4.65
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans with coronary artery disease identified the mir-4745-3p as a biomarker for recurrent myocardial infarction risk, finding it was downregulated in whole blood of patients with recurrent MI compared to stable CAD patients after percutaneous coronary intervention, with this differential expression achieving significance after false-discovery rate correction in a replication cohort [Onuoha et al. DOI:10.1111/cts.13307].