Basic Information

Symbol
hsa-mir-4748
RNA class
miRNA miRNA hairpin
Alias
MIR4748 MicroRNA 4748 Hsa-Mir-4748 MIMAT0019884 Hsa-MiR-4748 MI0017387 Mir-4748
Location (GRCh38)
20:34990400-34990472
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4748
Sequence length
82 nt
GC content
0.5854

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-31.90 kcal/mol
Thermodynamic ensemble
Free energy: -34.21 kcal/mol
Frequency: 0.0234
Diversity: 10.26
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((((.((.(((((.(((.((((((..(.((....)).).)))))).))).))))).)))).))).......)))))
Thermodynamic Ensemble Prediction
{(((((((((.((,(((((.{((.((((((..{.((....)).,.)))))).))}.))))))),)).))).......))))}
Forensic Context

A study in humans identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the mir-4748 being one of the miRNAs downregulated in hypertrophic scar tissue compared to normal tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-4748 was differentially expressed and shared across two pairs of monozygotic twins, as identified through miRNA microarray analysis of blood samples from 18 twin pairs, with the differential expression profiles validated by qRT-PCR for selected miRNAs, indicating its potential role as a biomarker for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].