Basic Information

Symbol
hsa-mir-4769
RNA class
miRNA miRNA hairpin
Alias
MIR4769 MicroRNA 4769 Hsa-Mir-4769 Hsa-MiR-4769-5p Hsa-MiR-4769-3p MIMAT0019923 MIMAT0019922 MI0017410
Location (GRCh38)
9:134379411-134379472
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4769
Sequence length
77 nt
GC content
0.5584

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-38.10 kcal/mol
Thermodynamic ensemble
Free energy: -38.70 kcal/mol
Frequency: 0.3763
Diversity: 3.80
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((((((((((((.((((.((.((((.(((((...........))))))))).)))))).))))..))))))))..
Thermodynamic Ensemble Prediction
..((((((((((((.((((.((.((((.(((((...........))))))))).)))))).))))..))))))))..
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like the mir-4769-5p showing altered expression patterns in human skin tissue samples post-burn and in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-4769-5p was differentially expressed and shared across two pairs of monozygotic twins, suggesting its potential role as a biomarker for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].