Forensic Context

A study in humans demonstrated that the miR-125b-1-3p is downregulated in septic shock patients compared to healthy controls [Li et al. DOI:10.1038/s41598-025-89946-6]. In separate human skin research, the miR-125b-1-3p was identified as differentially expressed, with its downregulation noted in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in Sprague-Dawley rats demonstrated that the miR-125b-1-3p was upregulated 1.99-fold in cardiac tissue one hour after isoproterenol injection, as identified by deep miRNA sequencing [Hosoya et al. DOI:10.1016/J.Legalmed.2024.102475].