Basic Information

Symbol
hsa-mir-485
RNA class
miRNA miRNA hairpin
Alias
MIR485 MicroRNA 485 Hsa-MiR-485-3p Hsa-MiR-485-5p Hsa-Mir-485 MIRN485 Hsa-Mir-154-P15_pre MIMAT0002175 MIMAT0002176 MI0002469 Mir-485
Location (GRCh38)
12:57519163-57519259
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-485
Sequence length
73 nt
GC content
0.4795

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-33.60 kcal/mol
Thermodynamic ensemble
Free energy: -35.12 kcal/mol
Frequency: 0.0848
Diversity: 3.96
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in human trauma patients demonstrated that the mir-485 was significantly upregulated in circulating T cells during the injury stage compared to the recovery stage and was identified as a hub miRNA regulating a miRNA-mRNA interactome predominantly involved in the chemokine signaling pathway [Rau et al. DOI:10.2147/JIR.S375881]. A study in humans demonstrated that the mir-485 was upregulated in the plasma of coronary artery disease patients compared to controls and was identified as a potential biomarker for the condition [Zhong et al. DOI:10.1002/jcla.23020]. In mice, research on ionizing radiation-induced thymus injury identified the mir-485 as a down-regulated known miRNA in the exposed thymus [Chen et al. DOI:10.1080/09553002.2016.1207821].