Basic Information

Symbol
hsa-mir-492
RNA class
miRNA miRNA hairpin
Alias
MIR492 MicroRNA 492 Hsa-Mir-492 Hsa-MiR-492 MIRN492 MIMAT0002812 MI0003131
Location (GRCh38)
12:94834398-94834513
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Cause of death analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-492
Sequence length
116 nt
GC content
0.5259

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-40.30 kcal/mol
Thermodynamic ensemble
Free energy: -41.84 kcal/mol
Frequency: 0.0818
Diversity: 6.37
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((.((((((.........((.(((.(..((.(((((((((((...((((((((.............))))))))))))))))))).))..).))).))...)))))).))...
Thermodynamic Ensemble Prediction
,,.((.((((((.........((.(((.(..((.(((((((((((...((((((((.,........,..))))))))))))))))))).))..).))).))...)))))).)).,,
Forensic Context

A study in humans evaluating nine candidate precursor microRNA single nucleotide polymorphisms in major blunt trauma patients found that the mir-492 rs2289030C/G was one of the evaluated SNPs but demonstrated no significant association with sepsis morbidity rate or multiple organ dysfunction scores in the screening cohort [Zhang et al. DOI:10.1097/SLA.0000000000000687]. A study in humans demonstrated that the mir-492 is a diagnostic biomarker for myocardial infarction, being upregulated in MI [Shirvani Samani et al. DOI:10.3390/jcm11010005].