Basic Information
Symbol
hsa-miR-492
RNA class
miRNA
mature miRNA
Alias
hsa-miR-492
MIR492
MicroRNA 492
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
Mechanical injury analysis
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-40.30 kcal/mol
Thermodynamic ensemble
Free energy:
-41.84 kcal/mol
Frequency:
0.0818
Diversity:
6.37
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((.((((((.........((.(((.(..((.(((((((((((...((((((((.............))))))))))))))))))).))..).))).))...)))))).))...
Thermodynamic Ensemble Prediction
,,.((.((((((.........((.(((.(..((.(((((((((((...((((((((.,........,..))))))))))))))))))).))..).))).))...)))))).)).,,
Forensic Context
A study in humans evaluating nine candidate precursor microRNA single nucleotide polymorphisms in major blunt trauma patients found that the miR-492 rs2289030C/G was one of the evaluated SNPs but demonstrated no significant association with sepsis morbidity rate or multiple organ dysfunction scores in the screening cohort [Zhang et al. DOI:10.1097/SLA.0000000000000687]. A study in humans demonstrated that the miR-492 is a diagnostic biomarker for myocardial infarction, being upregulated in MI [Shirvani Samani et al. DOI:10.3390/jcm11010005].