Basic Information

Symbol
hsa-miR-496
RNA class
miRNA mature miRNA
Alias
hsa-miR-496 MIR496 MicroRNA 496
Location (GRCh38)
-
Forensic tag(s)
Other applications
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-496
Sequence length
22 nt
GC content
0.4091

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.90 kcal/mol
Thermodynamic ensemble
Free energy: -44.65 kcal/mol
Frequency: 0.3056
Diversity: 4.31
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((((((...(((((.((((.((((((((.(((((..(((((((((........)))))))))..))))).)))))))).)))))))))........))))))
Forensic Context

A study in human cell lines and peripheral blood mononuclear cells (PBMCs) demonstrated that the miR-496 directly targets two cooperative sites in the mTOR 3' UTR, reducing mTOR mRNA and protein levels, as well as downstream phospho-mTOR and phospho-p70S6K signaling in transfected HeLa-K cells [Rubie et al. DOI: 10.080/15384101.2016.1158360].