A study in humans identified the miR-500a-5p as a potential biomarker predicted to bind hsa_circRNA_104700, which was up-regulated in lung tissue and plasma from sepsis-induced ARDS patients [Guo et al. DOI:10.1016/j.lfs.2021.119566]. Separately, research in humans demonstrated that the miR-500a-5p was differentially expressed and shared across three pairs of monozygotic twins, supporting its role as a biomarker for distinguishing genetically identical individuals in forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].