Forensic Context

A study in preterm human newborns with early-onset sepsis demonstrated that hsa-miR-5010-5p was significantly up-regulated in cord blood plasma compared to controls [Janec et al. DOI:10.14712/fb2023069050173]. In a separate study of human patients with acute myocardial infarction, plasma exosomal hsa-miR-5010-5p was identified as an intermediate-abundance miRNA that was up-regulated in the coronary artery disease group compared to the AMI group and was part of an 18-miRNA panel with a diagnostic AUC of 0.87 for AMI detection [Guo et al. DOI:10.21037/atm-20-2337]. A study in humans demonstrated that the mir-5010-5p was upregulated 1.86-fold in postischemic left ventricular myocardium following cardioplegic arrest [Saddic et al. DOI:10.1152/physiolgenomics.00049.2015].