Basic Information

Symbol
hsa-mir-503
RNA class
miRNA miRNA hairpin
Alias
MIR503 MicroRNA 503 Hsa-MiR-503-5p Hsa-Mir-503 Hsa-MiR-503-3p MIRN503 Hsa-Mir-15-P2c_pre MIMAT0022925 MIMAT0002874 MI0003188 Mir-503
Location (GRCh38)
13:50048973-50049061
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-503
Sequence length
71 nt
GC content
0.5915

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-42.20 kcal/mol
Thermodynamic ensemble
Free energy: -43.53 kcal/mol
Frequency: 0.1150
Diversity: 5.35
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((.((((((((((((((.((.((..(((((.....))))))).)).)))))))))))))).))))))
Thermodynamic Ensemble Prediction
{(((((.((((((((((((((.((.(({.{{((,.....)))}))).)).)))))))))))))).)))))}
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs showing altered expression in human skin tissue samples post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the mir-503 was significantly increased in ischemic heart tissue three days after myocardial infarction induced by coronary artery ligation [Williams et al. DOI:10.1152/physiolgenomics.00041.2020].