Basic Information

Symbol
hsa-mir-505
RNA class
miRNA miRNA hairpin
Alias
MIR505 MicroRNA 505 Hsa-MiR-505-5p Hsa-MiR-505-3p Hsa-Mir-505 MIRN505 Hsa-Mir-505-V1_pre Hsa-Mir-505-V2_pre MIMAT0004776 MIMAT0002876 MI0003190 Mir-505
Location (GRCh38)
X:139924148-139924231
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-505
Sequence length
84 nt
GC content
0.5238

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-44.90 kcal/mol
Thermodynamic ensemble
Free energy: -45.27 kcal/mol
Frequency: 0.5490
Diversity: 1.65
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((((..((((.(((((((((((.((((.((((((((...........)))))))).)))).))))))))))).)))).)))))
Forensic Context

A study in humans demonstrated that the mir-505 was significantly upregulated in the serum of patients with mild traumatic brain injury (mTBI) at baseline compared to controls, with its expression progressively reducing at 24 and 48 hours post-injury [Polito et al. DOI:10.1007/s11033-020-05386-7]. In rhesus macaques subjected to whole thorax irradiation, the mir-505 was utilized as a feature in elastic net-based models for survival prediction, specifically in Day 15 three-group and four-group survival models forecasting whether an animal would die in less than 90 days, between 90 and 269 days, or survive the study [May et al. DOI:10.1038/s41598-022-16316-x].