Forensic Context

A study in humans demonstrated that the mir-505 was significantly upregulated in the serum of patients with mild traumatic brain injury (mTBI) at baseline compared to controls, with its expression progressively reducing at 24 and 48 hours post-injury [Polito et al. DOI:10.1007/s11033-020-05386-7]. In rhesus macaques subjected to whole thorax irradiation, the mir-505 was utilized as a feature in elastic net-based models for survival prediction, specifically in Day 15 three-group and four-group survival models forecasting whether an animal would die in less than 90 days, between 90 and 269 days, or survive the study [May et al. DOI:10.1038/s41598-022-16316-x].