Basic Information
Symbol
hsa-miR-5100
RNA class
miRNA
mature miRNA
Alias
hsa-miR-5100
MIR5100
MicroRNA 5100
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-47.40 kcal/mol
Thermodynamic ensemble
Free energy:
-48.52 kcal/mol
Frequency:
0.4658
Diversity:
3.22
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((....))(((((((.(((((.(((((((((((((...((.(((..((((((.(((.......))).))))))..)))))..))))))))...))))).....)))...)).)))))))
Thermodynamic Ensemble Prediction
{{....}}(((((((.(((({.(((((((((((((...((.(((..((((((.(((.......))).))))))..)))))..))))))))...))))).....))}...)).)))))))
Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the miR-5100 is a predicted targeted miRNA of the novel lncRNA 220, which is upregulated in hepatic tissues and Kupffer cells after LPS treatment and regulates autophagy and apoptosis via the miR-5101/PI3K/AKT/mTOR axis [Yang et al. DOI:10.3390/ijms241311210].