Basic Information

Symbol
hsa-mir-5189
RNA class
miRNA miRNA hairpin
Alias
MIR5189 MicroRNA 5189 Hsa-Mir-5189 MIMAT0027088 MIMAT0021120 MI0018168 Mir-5189
Location (GRCh38)
12:109833348-109833436
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-5189
Sequence length
114 nt
GC content
0.6754

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-56.10 kcal/mol
Thermodynamic ensemble
Free energy: -58.07 kcal/mol
Frequency: 0.0410
Diversity: 13.18
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((.((.((.....((((((.((..((((((((.(.(((((.(((.((((....((...))....))))))).))))).).))))))))...)).))))))....)))).))...
Thermodynamic Ensemble Prediction
(({((.{{.....((((((.((..((((((((.{.(((((.(((.((((.,..((...))..,.))))))).))))).}.))))))))...)).)))))),,..)))).))...
Forensic Context

A study in humans demonstrated that the mir-5189-5p was downregulated (-4.01 fold) in postischemic left ventricular myocardium following acute ischemia during cardiac surgery [Saddic et al. DOI:10.1152/physiolgenomics.00049.2015].