Basic Information

Symbol
hsa-let-7f-1
RNA class
miRNA miRNA hairpin
Alias
MIRLET7F1 MicroRNA Let-7f-1 Hsa-Let-7f-1-3p Hsa-Let-7f-5p Hsa-Let-7f-1 MIRNLET7F1 Hsa-Let-7-P2b1_pre MIMAT0004486 MIMAT0000067 MI0000067 Let-7f-1 LET7F1
Location (GRCh38)
9:94176347-94176433
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-let-7f-1
Sequence length
87 nt
GC content
0.4023

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-42.30 kcal/mol
Thermodynamic ensemble
Free energy: -42.99 kcal/mol
Frequency: 0.3249
Diversity: 2.40
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((.(.((((((((((((((((((((((((((((((.....))))))).........))))))))))))))))))))))).)))))
Thermodynamic Ensemble Prediction
{(((.(.((((((((((((((((((((((((((((((.....))))))).........))))))))))))))))))))))).))))}
Forensic Context

A study in young human patients with acute coronary syndrome identified the let-7f-1 as down-regulated in patients with ST-segment elevated myocardial infarction (STEMI) via small RNA sequencing [Tong et al. DOI:10.3390/ijms19051467]. A study in human tissues demonstrated that the primer-extension quantitative PCR assay enabled sensitive and specific quantification of microRNAs, including the let-7f-1, which showed substantial expression across five profiled human tissues [Raymond et al. DOI:10.1261/rna.2148705].