Basic Information

Symbol
hsa-mir-5194
RNA class
miRNA miRNA hairpin
Alias
MIR5194 MicroRNA 5194 Hsa-Mir-5194 MIMAT0021125 MI0018173 Mir-5194
Location (GRCh38)
14:27633205-27633278
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-5194
Sequence length
120 nt
GC content
0.4500

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-37.20 kcal/mol
Thermodynamic ensemble
Free energy: -39.91 kcal/mol
Frequency: 0.0123
Diversity: 15.19
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((..((((((.......((((..((((.(((..((((((((.(((.((((((((...........)))))))))))...)))))))).))).)))).)))).....))).))).)))
Thermodynamic Ensemble Prediction
...{{..((((((.......((((..((((.(((..((((((((..{(.((((((((..{......}.)))))))),}}...)))))))).))).)))).)))).....))).))}.}}.
Forensic Context

A study in human peripheral blood mononuclear cells demonstrated that the mir-5194 was significantly upregulated at a 1 Gy radiation dose, identifying it as a potential biomarker for radiation response [Lee et al. DOI:10.1155/2014/456323]. A subsequent review confirmed this finding, reporting the mir-5194 as upregulated in human PBMCs at 1 Gy 24h post-irradiation, supporting its role in dose estimation [Jia & Wang DOI:10.3389/fcell.2022.861451].