Basic Information
Symbol
hsa-miR-5194
RNA class
miRNA
mature miRNA
Alias
hsa-miR-5194
MIR5194
MicroRNA 5194
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-37.20 kcal/mol
Thermodynamic ensemble
Free energy:
-39.91 kcal/mol
Frequency:
0.0123
Diversity:
15.19
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((..((((((.......((((..((((.(((..((((((((.(((.((((((((...........)))))))))))...)))))))).))).)))).)))).....))).))).)))
Thermodynamic Ensemble Prediction
...{{..((((((.......((((..((((.(((..((((((((..{(.((((((((..{......}.)))))))),}}...)))))))).))).)))).)))).....))).))}.}}.
Forensic Context
A study in human peripheral blood mononuclear cells demonstrated that the miR-5194 was significantly upregulated at a 1 Gy radiation dose, identifying it as a potential biomarker for radiation response [Lee et al. DOI:10.1155/2014/456323]. A subsequent review confirmed this finding, reporting the miR-5194 as upregulated in human PBMCs at 1 Gy 24h post-irradiation, supporting its role in dose estimation [Jia & Wang DOI:10.3389/fcell.2022.861451].