Basic Information

Symbol
hsa-mir-520a
RNA class
miRNA miRNA hairpin
Alias
MIR520A MicroRNA 520a Hsa-MiR-520a-3p Hsa-MiR-520a-5p Hsa-Mir-520a MIRN520A Hsa-Mir-430-P21_pre MIMAT0002834 MIMAT0002833 MI0003149
Location (GRCh38)
Forensic tag(s)
Tissue/body fluid identification Wound age identification

Sequence & Structure

Transcript ID
hsa-mir-520a
Sequence length
85 nt
GC content
0.4824

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.20 kcal/mol
Thermodynamic ensemble
Free energy: -49.79 kcal/mol
Frequency: 0.3856
Diversity: 2.91
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((((((((.(((..((((((((((((((((((((.{(.((...)).)}.))))))))))))))))))))..))).)))))))))
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the mir-520a noted as a general miRNA with target genes SUV39H1 and CXCL8, though it was mentioned in introductory discussion and not experimentally studied within the provided context [Siu et al. DOI:10.1111/wrr.13100]. A review of miRNA profiling for forensic body fluid identification in humans noted that the mir-520a is considered a pregnancy-associated biomarker, detected in maternal plasma [Silva et al. DOI:10.1016/J.Fsigen.2014.09.002].