Basic Information

Symbol
hsa-mir-520b
RNA class
miRNA miRNA hairpin
Alias
MIR520B MicroRNA 520b Hsa-Mir-520b MIRN520B Hsa-Mir-430-P22_pre Hsa-MiR-520b-5p Hsa-MiR-520b-3p MIMAT0037325 MIMAT0002843 Hsa-MiR-520b MI0003155
Location (GRCh38)
X:45747015-45747124
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-520b
Sequence length
61 nt
GC content
0.4590

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.50 kcal/mol
Thermodynamic ensemble
Free energy: -36.00 kcal/mol
Frequency: 0.4417
Diversity: 2.54
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the mir-520b was upregulated 6.51-fold in denatured dermis from deep partial-thickness burn patients compared to paired normal skin, a finding consistent with its reported upregulation four days post-burn in similar human burn samples [Liang et al. DOI:10.1016/j.burns.2011.10.014][Siu et al. DOI:10.1111/wrr.13100].