Basic Information

Symbol
hsa-mir-520c
RNA class
miRNA miRNA hairpin
Alias
MIR520C MicroRNA 520c Hsa-MiR-520c-3p Hsa-MiR-520c-5p Hsa-Mir-520c Hsa-MiR-518d-5p Hsa-MiR-526a MIRN520C Hsa-Mir-430-P23_pre MIMAT0005455 MIMAT0002846 MI0003158 hsa-mir-526a
Location (GRCh38)
5:168768146-168768255
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Chronological age estimation
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-520c
Sequence length
87 nt
GC content
0.4483

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-48.90 kcal/mol
Thermodynamic ensemble
Free energy: -49.91 kcal/mol
Frequency: 0.1934
Diversity: 3.48
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((.((..(((((((((((((((((((((((....(((...)))..)))))))))))))))))))))))..)).))))))))
Thermodynamic Ensemble Prediction
{(((((((.((.,(((((((((((((((((((((((....(({...)))..))))))))))))))))))))))),.)).)))))))}
Forensic Context

A study in human cardiac stromal cells from arrhythmogenic cardiomyopathy (ACM) patients identified the mir-520c-3p as significantly higher expressed (>4-fold) in ACM samples during an initial screen, but its expression was below detection levels in all validation samples [Rainer et al. DOI:10.1186/s12864-018-4876-6]. Separately, a study in human peripheral blood from physiologically unaffected individuals found the mir-520c-3p was significantly positively correlated with age in a microarray analysis [Meder et al. DOI:10.1373/clinchem.2014.224238].