Basic Information

Symbol
hsa-mir-520d
RNA class
miRNA miRNA hairpin
Alias
MIR520D MicroRNA 520d Hsa-MiR-520d-5p Hsa-Mir-520d Hsa-MiR-520d-3p MIRN520D Hsa-Mir-430-P24_pre MIMAT0002856 MIMAT0002855 MI0003164
Location (GRCh38)
Forensic tag(s)
Mechanical injury analysis

Sequence & Structure

Transcript ID
hsa-mir-520d
Sequence length
87 nt
GC content
0.4253

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-44.20 kcal/mol
Thermodynamic ensemble
Free energy: -45.13 kcal/mol
Frequency: 0.2218
Diversity: 5.88
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((((((((.((..(((((((((((.((((((....(((...)))..)))))).)))))))))))..)).)))))))))))))
Thermodynamic Ensemble Prediction
{((((((((((((.((..(((((((((((.((((((....(({...)))..)))))).)))))))))))..)).))))))))))))}
Forensic Context

A study in humans identified the mir-520d-3p as a diagnostic microRNA upregulated in serum following mild traumatic brain injury, where it targets 1566 genes and is part of a robust signaling signature involving MAPK, TGF-β, and other pathways that is concomitantly reflected across serum, plasma, and saliva [Matyasova et al. DOI:10.4149/gpb_2021038].