Basic Information

Symbol
hsa-mir-520h
RNA class
miRNA miRNA hairpin
Alias
MIR520H MicroRNA 520h Hsa-Mir-520h Hsa-MiR-520h MIRN520H Hsa-Mir-430-P27b_pre Hsa-Mir-430-P27a_pre MIMAT0002867 MI0003175
Location (GRCh38)
Forensic tag(s)
Other applications

Sequence & Structure

Transcript ID
hsa-mir-520h
Sequence length
88 nt
GC content
0.4318

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.90 kcal/mol
Thermodynamic ensemble
Free energy: -39.74 kcal/mol
Frequency: 0.2998
Diversity: 4.03
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.((.(((((..((((((((((((((((..(((((.............))))))))))))).))))))))))))).)).)))))
Thermodynamic Ensemble Prediction
{((((.((.(((({.,((((((((((((((((..(((((.{{.......},.))))))))))))))))))))))))))).)).))))}
Forensic Context

A review of human studies indicates that the mir-520h is considered a pregnancy-associated biomarker detected in maternal plasma and highly expressed in serum during pregnancy [Silva et al. DOI:10.1016/J.Fsigen.2014.09.002]. An experimental study in human cord blood hematopoietic stem cells from twins demonstrated that the mir-520h showed high differences in expression in both fraternal and identical twins and was placed in a group where environmental factors had a more significant effect than genetics [Ajami et al. DOI:10.22074/cellj.2019.5683].