Basic Information

Symbol
hsa-mir-532
RNA class
miRNA miRNA hairpin
Alias
MIR532 MicroRNA 532 Hsa-MiR-532-5p Hsa-MiR-532-3p Hsa-Mir-532 MIRN532 Hsa-Mir-188-P2_pre MIMAT0004780 MIMAT0002888 MI0003205 Mir-532
Location (GRCh38)
1:198859044-198859153
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Cause of death analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-532
Sequence length
91 nt
GC content
0.5385

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-30.80 kcal/mol
Thermodynamic ensemble
Free energy: -31.64 kcal/mol
Frequency: 0.2546
Diversity: 9.25
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
......((((.((((.((.((.((((((.((((.(((..((.,...........}}..))).)))).)))))).)).)).)))).))))..
Forensic Context

A study in humans demonstrated that the mir-532 was less abundant in pericardial fluid from ST-segment elevation myocardial infarction patients compared to controls and has been linked with anti-fibrotic effects [Silva et al. DOI:10.3390/ijms25158329]. A study in mice demonstrated that splenic CD11b+ monocytes from burn-injured animals exhibited differential miRNA expression, with miR-532-3p being significantly induced by burn injury according to microarray analysis, though RT-qPCR validation showed no significant influence on its expression [Liu et al. DOI:10.1111/iwj.14288].