Basic Information

Symbol
hsa-mir-548ap
RNA class
miRNA miRNA hairpin
Alias
MIR548AP MicroRNA 548ap Hsa-Mir-548ap Hsa-MiR-548ap-3p MIMAT0021038 MIMAT0021037 MI0017875
Location (GRCh38)
7:101159473-101159555
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-548ap
Sequence length
96 nt
GC content
0.3125

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-32.10 kcal/mol
Thermodynamic ensemble
Free energy: -32.95 kcal/mol
Frequency: 0.2508
Diversity: 3.88
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
...{{{(..((((((((((.(((((((((((.(((.(((((.(((......))).))))).))).)))))))))))))))))))))..))}}....
Forensic Context

A study in humans identified the mir-548ap-5p as a circulating microRNA significantly correlated with all-cause mortality and as an independent prognostic factor for overall survival in acute myocardial infarction patients over a 60-month follow-up period, with an AUC greater than 0.75 for survival prediction [Wang et al. DOI:10.1186/s40364-024-00690-x].