Basic Information

Symbol
hsa-mir-541
RNA class
miRNA miRNA hairpin
Alias
MIR541 MicroRNA 541 Hsa-MiR-541-5p Hsa-MiR-541-3p Hsa-Mir-541 MIRN541 Hsa-Mir-541_pre MIMAT0004920 MIMAT0004919 MI0005539 Mir-541
Location (GRCh38)
2:50696172-50696262
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Time since deposition estimation
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-541
Sequence length
84 nt
GC content
0.5357

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.80 kcal/mol
Thermodynamic ensemble
Free energy: -31.36 kcal/mol
Frequency: 0.0799
Diversity: 7.77
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((.(((((...((((((((.((((.(..((((((....((((...))))))))))).))))))))))))...)))))..))).
Thermodynamic Ensemble Prediction
{((.(((((...((((((((.((((.{..((((,({,..,(((...))))))))))}.))))))))))))...)))))..})}.
Forensic Context

A study in humans identified the mir-541 as a biomarker for recurrent myocardial infarction risk, where it was downregulated in whole blood of patients with recurrent MI after percutaneous coronary intervention and remained significant after false-discovery rate correction, though it was not significantly different in plasma [Onuoha et al. DOI:10.1111/cts.13307]. A study in mice and humans demonstrated that the mir-541 was evaluated for estimating the deposition time of bloodstains but could not be applied [Song et al. DOI:10.1007/s00414-023-03091-1].