Basic Information

Symbol
hsa-mir-542
RNA class
miRNA miRNA hairpin
Alias
MIR542 MicroRNA 542 Hsa-MiR-542-5p Hsa-MiR-542-3p Hsa-Mir-542 MIRN542 Hsa-Mir-542-V1_pre Hsa-Mir-542-V2_pre MIMAT0003340 MIMAT0003389 MI0003686 Mir-542
Location (GRCh38)
X:50008431-50008514
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-542
Sequence length
97 nt
GC content
0.4742

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.90 kcal/mol
Thermodynamic ensemble
Free energy: -36.36 kcal/mol
Frequency: 0.0942
Diversity: 5.13
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
....((((((((...((((..((((...(((((((((.(((....)))..)))))))))...))))..))))...))))))))..............
Thermodynamic Ensemble Prediction
..,.((((((((...((((..(((({{.(((((((((.(((....)))..)))))))))}}.))))..))))...))))))))..............
Forensic Context

A study in humans demonstrated that hsa-miR-542-5p was significantly upregulated in the plasma of acute myocardial infarction patients compared to healthy controls, identifying it as a potential biomarker for MI [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. A separate review of human studies reported that hsa-miR-542-5p is upregulated in burn hypertrophic scar tissue versus normal skin and is also upregulated in venous ulcers compared to normal skin and acute wounds [Siu et al. DOI:10.1111/wrr.13100].