Basic Information

Symbol
hsa-mir-548ad
RNA class
miRNA miRNA hairpin
Alias
MIR548AD MicroRNA 548ad Hsa-Mir-548ad Hsa-MiR-548ad-5p Hsa-MiR-548ad-3p MIMAT0018946 MIMAT0032114 MI0016770
Location (GRCh38)
Forensic tag(s)
Sudden cardiac death diagnosis

Sequence & Structure

Transcript ID
hsa-mir-548ad
Sequence length
82 nt
GC content
0.3659

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-42.00 kcal/mol
Thermodynamic ensemble
Free energy: -43.03 kcal/mol
Frequency: 0.1874
Diversity: 3.41
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the mir-548ad-5p was among the top ten upregulated circulating miRNAs in patients with acute myocardial infarction compared to non-AMI controls, as identified through RNA sequencing and validated by qRT-PCR [Zhong et al. DOI:10.1002/jcla.23099].