Basic Information

Symbol
hsa-mir-1270
RNA class
miRNA miRNA hairpin
Alias
MIR1270 MicroRNA 1270 Hsa-Mir-1270-2 Hsa-Mir-1270 Hsa-MiR-1270 MicroRNA 1270-2 MicroRNA 1270-1 MIR1270-1 MIR1270-2 MIRN1270 Hsa-Mir-1270_pre Hsa-Mir-1270-1 MIMAT0005924 MI0006407 Mir-1270
Location (GRCh38)
1:26554542-26554593
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1270
Sequence length
83 nt
GC content
0.3976

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.30 kcal/mol
Thermodynamic ensemble
Free energy: -35.02 kcal/mol
Frequency: 0.3100
Diversity: 2.54
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((.(((((((((..(((((((.(((((((((.(((((........)))))))))))))).)))))))..))))))))).))..
Thermodynamic Ensemble Prediction
{{.(((((((((..(((((((.(((((((((.(((((........)))))))))))))).)))))))..))))))))).)}..
Forensic Context

A study in humans demonstrated that the mir-1270 was not significantly influenced by age or sex when tested using a web-based application designed to assess confounding factors for miRNA signatures [Meder et al. DOI:10.1373/clinchem.2014.224238]. In a separate investigation, RNA sequencing of plasma from coronary artery disease patients identified the mir-1270 as one of the top ten upregulated microRNAs, and its expression profile was validated as a potential diagnostic biomarker for the disease [Zhong et al. DOI:10.1002/jcla.23020].