Basic Information

Symbol
hsa-mir-548ax
RNA class
miRNA miRNA hairpin
Alias
MIR548AX MicroRNA 548ax Hsa-Mir-548ax Hsa-MiR-548ax MIMAT0022474 MI0019286
Location (GRCh38)
1:37500935-37500994
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-548ax
Sequence length
73 nt
GC content
0.3973

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.80 kcal/mol
Thermodynamic ensemble
Free energy: -45.24 kcal/mol
Frequency: 0.0974
Diversity: 4.11
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((((((((((((((((((((((((((((((........))))).)))))))))))))))))))))))))..
Thermodynamic Ensemble Prediction
..((((((((((((((((((((((((((((((........)))))))))))))))))))))))))))))))..
Forensic Context

A study in humans demonstrated that the C allele of the mir-548ax rs1061541 was a protective factor against non-small-cell lung cancer (allele odds ratio=0.22) [Zheng et al. DOI:10.2147/CMAR.S163395]. A study in humans demonstrated that the mir-548ax was differentially expressed and shared across two pairs of monozygotic twins, with its expression profile analyzed via miRNA microarray and validated by qRT-PCR, indicating its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].