Basic Information
Symbol
hsa-miR-548ax
RNA class
miRNA
mature miRNA
Alias
hsa-miR-548ax
MIR548AX
MicroRNA 548ax
Location (GRCh38)
-
Forensic tag(s)
Sudden death from respiratory system disease
Individual identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.80 kcal/mol
Thermodynamic ensemble
Free energy:
-45.24 kcal/mol
Frequency:
0.0974
Diversity:
4.11
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A study in humans demonstrated that the C allele of the miR-548ax rs1061541 was a protective factor against non-small-cell lung cancer (allele odds ratio=0.22) [Zheng et al. DOI:10.2147/CMAR.S163395]. A study in humans demonstrated that the miR-548ax was differentially expressed and shared across two pairs of monozygotic twins, with its expression profile analyzed via miRNA microarray and validated by qRT-PCR, indicating its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].