Basic Information

Symbol
hsa-mir-548bc
RNA class
miRNA miRNA hairpin
Alias
MIR548BC MicroRNA 548BC Hsa-Mir-548bc MIMAT0039765 MI0032315
Location (GRCh38)
Forensic tag(s)
Drug abuse diagnoses

Sequence & Structure

Transcript ID
hsa-mir-548bc
Sequence length
110 nt
GC content
0.3545

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-50.20 kcal/mol
Thermodynamic ensemble
Free energy: -51.47 kcal/mol
Frequency: 0.1269
Diversity: 8.00
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in human postmortem brain tissue from individuals with alcohol use disorder (AUD) demonstrated that the mir-548bc was downregulated in ethanol-exposed human embryonic stem cell-derived cortical interneurons [Lim et al. DOI:10.1038/s41398-021-01635-w].