Basic Information
Symbol
hsa-miR-1270
RNA class
miRNA
mature miRNA
Alias
hsa-miR-1270
MIR1270
MicroRNA 1270
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.30 kcal/mol
Thermodynamic ensemble
Free energy:
-35.02 kcal/mol
Frequency:
0.3100
Diversity:
2.54
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A study in humans demonstrated that the miR-1270 was not significantly influenced by age or sex when tested using a web-based application designed to assess confounding factors for miRNA signatures [Meder et al. DOI:10.1373/clinchem.2014.224238]. In a separate investigation, RNA sequencing of plasma from coronary artery disease patients identified the miR-1270 as one of the top ten upregulated microRNAs, and its expression profile was validated as a potential diagnostic biomarker for the disease [Zhong et al. DOI:10.1002/jcla.23020].