Basic Information

Symbol
hsa-mir-1271
RNA class
miRNA miRNA hairpin
Alias
MIR1271 MicroRNA 1271 Hsa-MiR-1271-5p Hsa-MiR-1271-3p Hsa-Mir-1271 MIRN1271 Hsa-Mir-1271_pre MIMAT0022712 MIMAT0005796 MI0003814
Location (GRCh38)
Forensic tag(s)
Sudden cardiac death diagnosis Wound age identification

Sequence & Structure

Transcript ID
hsa-mir-1271
Sequence length
86 nt
GC content
0.5116

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-51.80 kcal/mol
Thermodynamic ensemble
Free energy: -52.28 kcal/mol
Frequency: 0.4570
Diversity: 1.95
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
..(((((..(((((((((((((.(((((.(((((((((((....))))))))))).))))).)))))))))))))..))).))...
Forensic Context

A study in humans demonstrated that the mir-1271 was significantly decreased in the plasma of acute myocardial infarction patients compared to healthy controls, as identified by next-generation sequencing [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. A separate review of human studies reported that the mir-1271 was downregulated 24 hours post-injury in skin wounds compared to unwounded skin [Siu et al. DOI:10.1111/wrr.13100].